Publications in 2017

Research

Maternal haemodynamics in normal pregnancies and in pregnancies affected by pre-eclampsia. Stott D, Nzelu O, Nicolaides KH, Kametas NA. Ultrasound Obstet Gynecol. 2017 Aug 10. doi: 10.1002/uog.18835.
Intrafetal laser for embryo reduction from dichorionic triplets to dichorionic twins. Chaveeva P, Peeva G, Gil Pugliese S, Shterev A, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 Aug 9. doi: 10.1002/uog.18834.
ASPRE trial: effect of aspirin in prevention of preterm preeclampsia in subgroups of women according to their characteristics and medical and obstetrical history. Poon LC, Wright D, Rolnik DL, Syngelaki A, Delgado JL, Tsokaki T, Leipold G, Akolekar R, Shearing S, De Stefani L, Jani JC, Plasencia W, Evangelinakis N, Gonzalez-Vanegas O, Persico N, Nicolaides KH. Am J Obstet Gynecol. 2017 Aug 4. pii: S0002-9378(17)30929-8. doi: 10.1016/j.ajog.2017.07.038.
ASPRE trial: performance of screening for preterm pre-eclampsia. Rolnik DL, Wright D, Poon LC, Syngelaki A, O'Gorman N, de Paco Matallana C, Akolekar R, Cicero S, Janga D, Singh M, Molina FS, Persico N, Jani JC, Plasencia W, Papaioannou G, Tenenbaum-Gavish K, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 Jul 25. doi: 10.1002/uog.18816.
Predicting the Risk to Develop Preeclampsia in the First Trimester Combining Promoter Variant -98A/C of LGALS13 (Placental Protein 13), Black Ethnicity, Previous Preeclampsia, Obesity, and Maternal Age. Madar-Shapiro L, Karady I, Trahtenherts A, Syngelaki A, Akolekar R, Poon L, Cohen R, Sharabi-Nov A, Huppertz B, Sammar M, Juhasz K, Than NG, Papp Z, Romero R, Nicolaides KH, Meiri H. Fetal Diagn Ther. 2017 Jul 21. doi: 10.1159/000477933.
Evaluation of Abdominal Fetal Electrocardiography in Early Intrauterine Growth Restriction. Velayo CL, Funamoto K, Silao JNI, Kimura Y, Nicolaides K. Front Physiol. 2017 Jun 26;8:437. doi: 10.3389/fphys.2017.00437. eCollection 2017.
Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia. Rolnik DL, Wright D, Poon LC, O'Gorman N, Syngelaki A, de Paco Matallana C, Akolekar R, Cicero S, Janga D, Singh M, Molina FS, Persico N, Jani JC, Plasencia W, Papaioannou G, Tenenbaum-Gavish K, Meiri H, Gizurarson S, Maclagan K, Nicolaides KH. N Engl J Med. 2017;377:613-622.
Two-stage approach for risk estimation of fetal Trisomy 21 and other aneuploidies using computational intelligence systems. Neocleous AC, Syngelaki A, Nicolaides KH, Schizas CN. Ultrasound Obstet Gynecol. 2017 Jun 22. doi: 10.1002/uog.17558.
Association of chronic hypertension with birth of small-for-gestational-age neonate. Panaitescu AM, Baschat AA, Akolekar R, Syngelaki A, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 Jun 21. doi: 10.1002/uog.17553.
Maternal autoimmune disorders and fetal defects. Panaitescu AM, Nicolaides K. J Matern Fetal Neonatal Med. 2017 Jun 18:1-9. doi: 10.1080/14767058.2017.1326904.
Expanded conventional first trimester screening. Carmichael JB, Liu HP, Janik D, Hallahan TW, Nicolaides KH, Krantz DA. Prenat Diagn. 2017;37:802-807.
Competing risks model in screening for preeclampsia in twin pregnancies by maternal factors and biomarkers at 11-13 weeks' gestation. Francisco C, Wright D, Benkő Z, Syngelaki A, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 May 27. doi: 10.1002/uog.17531.
Competing risks model in screening for preeclampsia in twin pregnancies by maternal characteristics and medical history. Francisco C, Wright D, Benkő Z, Syngelaki A, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 May 15. doi: 10.1002/uog.17529.
Impaired placentation in women with chronic hypertension that develop preeclampsia. Panaitescu AM, Akolekar R, Kametas N, Syngelaki A, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 May 4. doi: 10.1002/uog.17517.
Chronic hypertension and adverse pregnancy outcome: a cohort study. Panaitescu AM, Syngelaki A, Prodan N, Akolekar R, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;50:228-235.
Analysis of cell-free DNA in maternal blood in screening for aneuploidies: updated meta-analysis. Gil MM, Accurti V, Santacruz B, Plana MN, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 Apr 11. doi: 10.1002/uog.17484.
Hidden high rate of pre-eclampsia in twin compared with singleton pregnancy. Francisco C, Wright D, Benkő Z, Syngelaki A, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;50:88-92.
Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations. O'Gorman N, Wright D, Poon LC, Rolnik DL, Syngelaki A, de Alvarado M, Carbone IF, Dutemeyer V, Fiolna M, Frick A, Karagiotis N, Mastrodima S, de Paco Matallana C, Papaioannou G, Pazos A, Plasencia W, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:756-760.
Protocol for the prospective validation study: 'Screening programme for pre-eclampsia' (SPREE). Tan MY, Koutoulas L, Wright D, Nicolaides KH, Poon LCY. Ultrasound Obstet Gynecol. 2017;50:175-179.
Cerclage for Short Cervix on Ultrasound in Singleton Gestations without Prior Spontaneous Preterm Birth: a Systematic Review and Meta-analysis of Trials using individual patient-level data. Berghella V, Ciardulli A, Rust OA, To M, Otsuki K, Althuisius S, Nicolaides K, Roman A, Saccone G. Ultrasound Obstet Gynecol. 2017 Mar 10. doi: 10.1002/uog.17457.
Effect of change in posture on maternal functional hemodynamics at 35-37 weeks' gestation. Guy GP, Ling HZ, Machuca M, Poon LC, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 Mar 13. doi: 10.1002/uog.17466.
Proposed clinical management of pregnancies after combined screening for pre-eclampsia at 35-37 weeks' gestation. Panaitescu AM, Wright D, Militello A, Akolekar R, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 Jan 29. doi: 10.1002/uog.17419.
Proposed clinical management of pregnancies after combined screening for pre-eclampsia at 19-24 weeks' gestation. Litwinska M, Wright D, Efeturk T, Ceccacci I, Nicolaides KH. Ultrasound Obstet Gynecol. 2017 Jan 29. doi: 10.1002/uog.17418.
Gestational disruptions in metabolic rhythmicity of the liver, muscle, and placenta affect fetal size. Papacleovoulou G, Nikolova V, Oduwole O, Chambers J, Vazquez-Lopez M, Jansen E, Nicolaides K, Parker M, Williamson C. FASEB J. 2017;31:1698-1708.
Repeat measurements of uterine artery pulsatility index, mean arterial pressure and serum placental growth factor at 12, 22 and 32 weeks in prediction of pre-eclampsia. Andrietti S, Carlucci S, Wright A, Wright D, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;50:221-227.
Accuracy of competing-risks model in screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation. O'Gorman N, Wright D, Poon LC, Rolnik DL, Syngelaki A, Wright A, Akolekar R, Cicero S, Janga D, Jani J, Molina FS, de Paco Matallana C, Papantoniou N, Persico N, Plasencia W, Singh M, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:751-755.
Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation and a short cervix: an updated meta-analysis of individual patient data. Romero R, Conde-Agudelo A, El-Refaie W, Rode L, Brizot ML, Cetingoz E, Serra V, Da Fonseca E, Abdelhafez MS, Tabor A, Perales A, Hassan SS, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:303-314.
Cervical length screening for prevention of preterm birth in singleton pregnancy with threatened preterm labor: systematic review and meta-analysis of randomized controlled trials using individual patient-level data. Berghella V, Palacio M, Ness A, Alfirevic Z, Nicolaides KH, Saccone G. Ultrasound Obstet Gynecol. 2017;49:322-329.
Performance of the neoBona test: a new paired-end massively parallel shotgun sequencing approach for cell-free DNA-based aneuploidy screening. Cirigliano V, Ordoñez E, Rueda L, Syngelaki A, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:460-464.
Monochorionic diamniotic twin pregnancy with selective fetal growth restriction Type II: sonographic and fetoscopic findings of poor prognosis. Gil Guevara E, Bower S, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;50:272-273.
Maternal cardiac function at 35-37 weeks' gestation: relationship with birth weight. Guy GP, Ling HZ, Machuca M, Poon LC, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:67-72.
Maternal cardiovascular function at 35-37 weeks' gestation: relation to maternal characteristics. Guy GP, Ling HZ, Garcia P, Poon LC, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:39-45.
Development of pre-eclampsia within 4 weeks of sFlt-1/PlGF ratio > 38: comparison of performance at 31-34 vs 35-37 weeks' gestation. Dragan I, Wright D, Fiolna M, Leipold G, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:209-212.
Proposed clinical management of pregnancies after combined screening for pre-eclampsia at 30-34 weeks' gestation. Wright D, Dragan I, Syngelaki A, Akolekar R, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:194-200.
Comparison of screening for pre-eclampsia at 31-34 weeks' gestation by sFlt-1/PlGF ratio and a method combining maternal factors with sFlt-1 and PlGF. Tan MY, Wright D, Koutoulas L, Akolekar R, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:201-208.
The role of aspirin dose on the prevention of preeclampsia and fetal growth restriction: systematic review and meta-analysis. Roberge S, Nicolaides K, Demers S, Hyett J, Chaillet N, Bujold E. Am J Obstet Gynecol. 2017;216:110-120.e6.
Screening for pre-eclampsia using sFlt-1/PlGF ratio cut-off of 38 at 30-37 weeks' gestation. Dragan I, Georgiou T, Prodan N, Akolekar R, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:73-77.
Maternal cardiac function at 35-37 weeks' gestation: prediction of pre-eclampsia and gestational hypertension. Guy GP, Ling HZ, Garcia P, Poon LC, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:61-66.
Metabolomic determination of pathogenesis of late-onset preeclampsia. Bahado-Singh RO, Syngelaki A, Mandal R, Graham SF, Akolekar R, Han B, Bjondahl TC, Dong E, Bauer S, Alpay-Savasan Z, Turkoglu O, Ogunyemi D, Poon LC, Wishart DS, Nicolaides KH. J Matern Fetal Neonatal Med. 2017;30:658-664.
Impact of holoprosencephaly, exomphalos, megacystis and increased nuchal translucency on first-trimester screening for chromosomal abnormalities. Syngelaki A, Guerra L, Ceccacci I, Efeturk T, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;50:45-48.
Accuracy of first-trimester combined test in screening for trisomies 21, 18 and 13. Santorum M, Wright D, Syngelaki A, Karagioti N, Nicolaides KH. Ultrasound Obstet Gynecol. 2017;49:714-720.
Can Staining of Damaged Proteins in Urine Effectively Predict Preeclampsia? Sammar M, Syngelaki A, Sharabi-Nov A, Nicolaides K, Meiri H. Fetal Diagn Ther. 2017;41:23-31.