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Early vaginal progesterone versus placebo in twin pregnancies for the prevention of spontaneous preterm birth: a randomized, double-blind trial.
Rehal A, Benkő Z, De Paco Matallana C, Syngelaki A, Janga D, Cicero S, Akolekar R, Singh M, Chaveeva P, Burgos J, Molina FS, Savvidou M, De La Calle M, Persico N, Quezada Rojas MS, Sau A, Greco E, O'Gorman N, Plasencia W, Pereira S, Jani JC, Valino N, Del Mar Gil M, Maclagan K, Wright A, Wright D, Nicolaides KH.
Am J Obstet Gynecol 2021;224:86.e1-86.e19. pdf -
Cervical pessary to prevent preterm birth in asymptomatic high-risk women: a systematic review and meta-analysis.
Conde-Agudelo A, Romero R, Nicolaides KH.
Am J Obstet Gynecol 2020;223:42-65.e2. pdf -
Good clinical practice advice: Role of ultrasound in the management of twin pregnancy.
FIGO Working Group on Good Clinical Practice in Maternal-Fetal Medicine.
Int J Gynaecol Obstet 2019;144:338-339. pdf -
Good clinical practice advice: Prediction of preterm labor and preterm premature rupture of membranes.
FIGO Working Group on Good Clinical Practice in Maternal-Fetal Medicine.
Int J Gynaecol Obstet 2019;144:340-346. pdf -
Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: updated indirect comparison meta-analysis.
Conde-Agudelo A, Romero R, Da Fonseca E, O'Brien JM, Cetingoz E, Creasy GW, Hassan SS, Erez O, Pacora P, Nicolaides KH.
Am J Obstet Gynecol 2018;219:10-25. pdf -
Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data.
Romero R, Conde-Agudelo A, Da Fonseca E, O'Brien JM, Cetingoz E, Creasy GW, Hassan SS, Nicolaides KH.
Am J Obstet Gynecol 2018;218:161-180. pdf -
There is insufficient evidence to claim that cerclage is the treatment of choice for patients with a cervical length <10 mm.
Romero R, Conde-Agudelo A, Nicolaides KH.
Am J Obstet Gynecol 2018;219:213-215. pdf -
Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation and a short cervix: an updated meta-analysis of individual patient data.
Romero R, Conde-Agudelo A, El-Refaie W, Rode L, Brizot ML, Cetingoz E, Serra V, Da Fonseca E, Abdelhafez MS, Tabor A, Perales A, Hassan SS, Nicolaides KH.
Ultrasound Obstet Gynecol 2017;49:303-14 pdf -
Is variation in copy number of the human beta-defensin gene cluster associated with preterm birth?
James C, Abujaber R, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides K, Hollox E, Peebles D.
Lancet DOI: 10.1016/S0140-6736(15)60362-2 pdf -
Chronic hypertension and adverse pregnancy outcomes: a cohort study.
Panaitescu AM, Syngelaki A, Prodan N, Akolekar R, Nicolaides KH.
Ultrasound Obstet Gynecol DOI: 10.1002/uog.17493 pdf -
Cervical length screening for prevention of preterm birth in singleton pregnancy with threatened preterm labor: systematic review and meta-analysis of randomized controlled trials using individual patient-level data.
Berghella V, Palacio M, Ness A, Alfirevic Z, Nicolaides KH, Saccone G.
Ultrasound Obstet Gynecol 2017;49:322-9 pdf -
Cerclage for Short Cervix on Ultrasound in Singleton Gestations without Prior Spontaneous Preterm Birth: a Systematic Review and Meta-analysis of Trials using individual patient-level data.
Berghella V, Ciardulli A, Rust OA, To M, Otsuki K, Althuisius S, Nicolaides K, Roman A, Saccone G.
Ultrasound Obstet Gynecol DOI: 10.1002/uog.17457 pdf -
Vaginal progesterone decreases preterm birth <34 weeks of gestation in women with a singleton pregnancy and a short cervix: an updated meta-analysis including data from the OPPTIMUM study.
Romero R, Nicolaides KH, Conde-Agudelo A, O'Brien JM, Cetingoz E, Da Fonseca E, Creasy GW, Hassan SS.
Ultrasound Obstet Gynecol 2016;48:308-17 pdf -
The effect of gestational age and cervical length measurements in the prediction of spontaneous preterm birth in twin pregnancies: an individual patient level meta-analysis.
Kindinger LM, Poon LC, Cacciatore S, MacIntyre DA, Fox NS, Schuit E, Mol BW, Liem S, Lim AC, Serra V, Perales A, Hermans F, Darzi A, Bennett P, Nicolaides KH, Teoh TG.
BJOG 2016;123:877-84 pdf -
Inverted Pyramid of Care.
Sonek JD, Kagan KO, Nicolaides KH.
Clin Lab Med 2016;36:305-17 pdf -
Cervical pessary placement for prevention of preterm birth in unselected twin pregnancies: a randomized controlled trial.
Nicolaides KH, Syngelaki A, Poon LC, de Paco Matallana C, Plasencia W, Molina FS, Picciarelli G, Tul N, Celik E, Lau TK, Conturso R.
Am J Obstet Gynecol 2016;214:3.e1-9 pdf -
Cervical cerclage for preterm birth prevention in twin gestation with short cervix: a retrospective cohort study.
Houlihan C, Poon LC, Ciarlo M, Kim E, Guzman ER, Nicolaides KH.
Ultrasound Obstet Gynecol 2016;48:752-6 pdf -
A Randomized Trial of a Cervical Pessary to Prevent Preterm Singleton Birth.
Nicolaides KH, Syngelaki A, Poon LC, Picciarelli G, Tul N, Zamprakou A, Skyfta E, Parra-Cordero M, Palma-Dias R, Rodriguez Calvo J.
N Engl J Med 2016;374:1044-52 pdf -
Fetal fraction of cell-free DNA in maternal plasma in the prediction of spontaneous preterm delivery.
Quezada MS, Francisco C, Dumitrascu-Biris D, Nicolaides KH, Poon LC.
Ultrasound Obstet Gynecol 2015;45:101-5 pdf -
Effectiveness of progestogens to improve perinatal outcome in twin pregnancies: an individual participant data meta-analysis.
Schuit E, Stock S, Rode L, Rouse DJ, Lim AC, Norman JE, Nassar AH, Serra V, Combs CA, Vayssiere C, Aboulghar MM, Wood S, Atetingaz E, Briery CM, Fonseca EB, Worda K, Tabor A, Thom EA, Caritis SN, Awwad J, Usta IM, Perales A.
BJOG 2015;122:27-37 pdf