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Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening.
Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O.
Ultrasound Obstet Gynecol 2005;25:221-6. -
Evidence-based obstetric ethics and informed decision-making by pregnant women about invasive diagnosis after first-trimester assessment of risk for trisomy 21.
Nicolaides KH, Chervenak FA, McCullough LB, Avgidou K, Papageorghiou A.
Am J Obstet Gynecol 2005;193:322-6. -
Down syndrome screening marker levels in women with a previous aneuploidy pregnancy.
Cuckle HS, Spencer K, Nicolaides KH.
Prenat Diagn 2005;25:47-50. -
Prospective first-trimester screening for trisomy 21 in 30,564 pregnancies.
Avgidou K, Papageorghiou A, Bindra R, Spencer K, Nicolaides KH.
Am J Obstet Gynecol 2005;192:1761-7. -
Screening for trisomy 21 in twins using first trimester ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years experience.
Spencer K, Nicolaides KH.
BJOG 2003;110:276-80. -
Ear length in trisomy 21 fetuses at 11-14 weeks of gestation.
Sacchini C, El-Sheikhah A, Cicero S, Rembouskos G, Nicolaides KH.
Ultrasound Obstet Gynecol 2003;22:460-3. -
Integrated ultrasound and biochemical screening for trisomy 21 using fetal nuchal translucency, absent fetal nasal bone, free beta-hCG and PAPP-A at 11 to 14 weeks.
Cicero S, Bindra R, Rembouskos G, Spencer K, Nicolaides KH.
Prenat Diagn 2003;23:306-10. -
One-stop clinic for assessment of risk for trisomy 21 at 11-14 weeks: a prospective study of 15 030 pregnancies.
Bindra R, Heath V, Liao A, Spencer K, Nicolaides KH.
Ultrasound Obstet Gynecol 2002;20:219-25. -
First-trimester screening for trisomy 21 in singleton pregnancies achieved by assisted reproduction.
Liao AW, Heath V, Kametas N, Spencer K, Nicolaides KH.
Hum Reprod 2001;16:1501-4. -
Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: an observational study.
Cicero S, Curcio P, Papageorghiou A, Sonek J, Nicolaides K.
Lancet 2001;358:1665-7. -
First trimester markers of trisomy 21 and the influence of maternal cigarette smoking status.
Spencer K, Ong CYT, Liao AWJ, Papademetriou D, Nicolaides KH.
Prenat Diagn 2000;20:852-3. -
First trimester prenatal diagnosis of trisomy 21 in discordant twins using fetal nuchal translucency thickness and maternal serum free beta-hCG and PAPP-A.
Spencer K, Nicolaides KH.
Prenat Diagn 2000;20:683-4. -
The influence of fetal sex in screening for trisomy 21 by fetal nuchal translucency, maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation.
Spencer K, Ong CY, Liao AW, Papademetriou D, Nicolaides KH.
Prenat Diagn 2000;20:673-5. -
Cardiac defects in chromosomally normal fetuses with abnormal ductus venosus blood flow at 10-14 weeks.
Matias A, Huggon I, Areias JC, Montenegro N, Nicolaides KH.
Ultrasound Obstet Gynecol 1999;14:307-10. -
Collagen type VI gene expression in the skin of trisomy 21 fetuses.
von Kaisenberg CS, Brand-Saberi B, Christ B, Vallian S, Farzaneh F, Nicolaides KH.
Obstet Gynecol 1998;91:319-23. -
UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal-translucency thickness at 10-14 weeks of gestation.
Snijders RJ, Noble P, Sebire N, Souka A, Nicolaides KH.
Lancet 1998;352:343-6. -
The umbilical artery pulsatility index in the first trimester: is there an association with increased nuchal translucency or chromosomal abnormality?
Brown R, Di Luzio L, Gomes C, Nicolaides KH.
Ultrasound Obstet Gynecol 1998;12:244-7. -
Down's syndrome screening with nuchal translucency.
Nicolaides KH, Sebire NJ, Snijders RJ.
Lancet 1997;349:438. -
Early prenatal diagnosis of triploidy.
Jauniaux E, Brown R, Snijders RJ, Noble P, Nicolaides KH.
Am J Obstet Gynecol 1997;176:550-4. -
Screening for trisomy 21 in twin pregnancies by maternal age and fetal nuchal translucency thickness at 10-14 weeks of gestation.
Sebire NJ, Snijders RJM, Hughes K, Sepulveda W, Nicolaides KH.
BJOG 1996;103:999-1003.