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Serum beta defensin concentration in the first trimester is related to genotype, and is higher in women who develop PPROM and deliver before 34 weeks.
James C, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides KH, Peebles D.
Arch Dis Child Fetal Neonatal Ed 2014;99 Suppl 1:A12. pdf -
Maternal plasma pentraxin 3 at 11 to 13 weeks of gestation in hypertensive disorders of pregnancy.
Akolekar R, Casagrandi D, Livanos P, Tetteh A, Nicolaides KH.
Prenat Diagn 2009;29:934-8.