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Serum beta defensin concentration in the first trimester is related to genotype, and is higher in women who develop PPROM and deliver before 34 weeks.
James C, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides KH, Peebles D.
Arch Dis Child Fetal Neonatal Ed 2014;99 Suppl 1:A12. pdf -
First trimester sex hormone-binding globulin and subsequent development of preeclampsia or other adverse pregnancy outcomes.
Spencer K, Yu CK, Rembouskos G, Bindra R, Nicolaides KH.
Hypertens Pregnancy 2005;24:303-11.