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Serum beta defensin concentration in the first trimester is related to genotype, and is higher in women who develop PPROM and deliver before 34 weeks.
James C, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides KH, Peebles D.
Arch Dis Child Fetal Neonatal Ed 2014;99 Suppl 1:A12. pdf -
Maternal serum progesterone-induced blocking factor at 11-13 weeks gestation in spontaneous early preterm delivery.
Beta J, Szekeres-Bartho J, Skyfta E, Akolekar R, Nicolaides KH.
Fetal Diagn Ther 2011;29:197-200.