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Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: updated indirect comparison meta-analysis.
Conde-Agudelo A, Romero R, Da Fonseca E, O'Brien JM, Cetingoz E, Creasy GW, Hassan SS, Erez O, Pacora P, Nicolaides KH.
Am J Obstet Gynecol 2018;219:10-25. pdf -
Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data.
Romero R, Conde-Agudelo A, Da Fonseca E, O'Brien JM, Cetingoz E, Creasy GW, Hassan SS, Nicolaides KH.
Am J Obstet Gynecol 2018;218:161-180. pdf -
There is insufficient evidence to claim that cerclage is the treatment of choice for patients with a cervical length <10 mm.
Romero R, Conde-Agudelo A, Nicolaides KH.
Am J Obstet Gynecol 2018;219:213-215. pdf -
Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation and a short cervix: an updated meta-analysis of individual patient data.
Romero R, Conde-Agudelo A, El-Refaie W, Rode L, Brizot ML, Cetingoz E, Serra V, Da Fonseca E, Abdelhafez MS, Tabor A, Perales A, Hassan SS, Nicolaides KH.
Ultrasound Obstet Gynecol 2017;49:303-14 pdf -
Cervical length screening for prevention of preterm birth in singleton pregnancy with threatened preterm labor: systematic review and meta-analysis of randomized controlled trials using individual patient-level data.
Berghella V, Palacio M, Ness A, Alfirevic Z, Nicolaides KH, Saccone G.
Ultrasound Obstet Gynecol 2017;49:322-9 pdf -
Cerclage for Short Cervix on Ultrasound in Singleton Gestations without Prior Spontaneous Preterm Birth: a Systematic Review and Meta-analysis of Trials using individual patient-level data.
Berghella V, Ciardulli A, Rust OA, To M, Otsuki K, Althuisius S, Nicolaides K, Roman A, Saccone G.
Ultrasound Obstet Gynecol DOI: 10.1002/uog.17457 pdf -
Vaginal progesterone decreases preterm birth <34 weeks of gestation in women with a singleton pregnancy and a short cervix: an updated meta-analysis including data from the OPPTIMUM study.
Romero R, Nicolaides KH, Conde-Agudelo A, O'Brien JM, Cetingoz E, Da Fonseca E, Creasy GW, Hassan SS.
Ultrasound Obstet Gynecol 2016;48:308-17 pdf -
The effect of gestational age and cervical length measurements in the prediction of spontaneous preterm birth in twin pregnancies: an individual patient level meta-analysis.
Kindinger LM, Poon LC, Cacciatore S, MacIntyre DA, Fox NS, Schuit E, Mol BW, Liem S, Lim AC, Serra V, Perales A, Hermans F, Darzi A, Bennett P, Nicolaides KH, Teoh TG.
BJOG 2016;123:877-84 pdf -
Cervical pessary placement for prevention of preterm birth in unselected twin pregnancies: a randomized controlled trial.
Nicolaides KH, Syngelaki A, Poon LC, de Paco Matallana C, Plasencia W, Molina FS, Picciarelli G, Tul N, Celik E, Lau TK, Conturso R.
Am J Obstet Gynecol 2016;214:3.e1-9 pdf -
Cervical cerclage for preterm birth prevention in twin gestation with short cervix: a retrospective cohort study.
Houlihan C, Poon LC, Ciarlo M, Kim E, Guzman ER, Nicolaides KH.
Ultrasound Obstet Gynecol 2016;48:752-6 pdf -
A Randomized Trial of a Cervical Pessary to Prevent Preterm Singleton Birth.
Nicolaides KH, Syngelaki A, Poon LC, Picciarelli G, Tul N, Zamprakou A, Skyfta E, Parra-Cordero M, Palma-Dias R, Rodriguez Calvo J.
N Engl J Med 2016;374:1044-52 pdf -
Successful induction of labor: prediction by pre-induction cervical length, angle of progression and cervical elastography.
Pereira S, Frick AP, Poon LC, Zamprakou A, Nicolaides KH.
Ultrasound Obstet Gynecol 2014;44:468-75 pdf -
In-vivo assessment of the biomechanical properties of the uterine cervix in pregnancy.
Mazza E, Parra-Saavedra M, Bajka M, Gratacos E, Nicolaides KH, Deprest J.
Prenat Diagn 2014;34:33-41 pdf -
In vivo assessment of the biomechanical properties of the uterine cervix in pregnancy.
Mazza E, Parra-Saavedra M, Bajka M, Gratacos E, Nicolaides K, Deprest J.
Prenat Diagn 2014;34:33-41 pdf -
Quantification of cervical elastography: a reproducibility study.
Molina FS, Gómez LF, Florido J, Padilla MC, Nicolaides KH.
Ultrasound Obstet Gynecol 2012;39:685-9 pdf -
Large loop excision of transformation zone and cervical length in the prediction of spontaneous preterm delivery.
Poon LC, Savvas M, Zamblera D, Skyfta E, Nicolaides KH.
BJOG 2012;119:692-8 -
First-trimester screening for spontaneous preterm delivery with maternal characteristics and cervical length.
Greco E, Gupta R, Syngelaki A, Poon LC, Nicolaides KH.
Fetal Diagn Ther 2012;31:154-61 pdf -
Vaginal micronized progesterone and the risk of preterm delivery in high-risk twin pregnancies - secondary analysis of a placebo-controlled randomized trial and meta-analysis.
Klein K, Rode L, Nicolaides K, Krampl-Bettelheim E, Tabor A.
Ultrasound Obstet Gynecol 2011;38:281-7 pdf -
Prevention of preterm delivery in twin gestations (PREDICT): A multicentre randomised placebo-controlled trial on the effect of vaginal micronised progesterone.
Rode L, Klein K, Nicolaides K, Krampl-Bettelheim E, Tabor A.
Ultrasound Obstet Gynecol 2011;38:272-80 pdf -
Prediction of spontaneous preterm delivery from endocervical length at 11 to 13 weeks.
Greco E, Lange A, Ushakov F, Calvo JR, Nicolaides KH.
Prenat Diagn 2011;31:84-9 pdf