- 1 in 5,000 births.
- ‘Double bubble’ sign as a result of an enlarged stomach and duodenal cap. Usually found >24 weeks’ gestation.
- Polyhydramnios >24 weeks’ gestation in 50% of cases.
- Chromosomal defects, mainly trisomy 21, are found in 30% of cases.
- Other defects, mainly cardiac, renal, vertebral, are found in 10-20% of cases.
- Detailed ultrasound examination, including echocardiography.
- Ultrasound scans every 2-3 weeks to monitor growth and assess amniotic fluid volume. Amniodrainage may be necessary if there is polyhydramnios and cervical shortening.
- Place: hospital with neonatal intensive care and pediatric surgery.
- Time: 38 weeks.
- Method: induction of labor aiming for vaginal delivery.
- Survival rate >95%.
- Isolated: no increased risk of recurrence.
- Part of trisomy 21: 1%.